Sepsis Is One of the Leading Causes of Death in the United States

• The incidence rate of hospitalizations with severe sepsis increased up to threefold in the last decade, according to a large scale retrospective study.

  (Source: National Institutes of Health)

• Mortality from sepsis is estimated to be greater than mortality from AIDS and breast cancer combined.

  (Source: National Institute of General Medical Sciences)

• Sepsis is the second leading cause of death in non-coronary ICUs, with a mortality rate of up to 45%.

  (Source: Society of Critical Care Medicine)

• For nearly 80% of patients, sepsis begins outside of the hospital.

  (Source: CDC)

• The pediatric mortality rate associated with sepsis is 25%, whereas the overall mortality rate for pediatric ICU patients ranges from 2% to 6%.

  (Source: Society of Critical Care Medicine)

• Patients with initially less severe sepsis made up the majority of sepsis deaths in an analysis of a nationally representative sample of hospitalizations.

  (Source: JAMA)

Improved Sepsis Detection Reduces Costs While Saving Lives

• Nearly one-quarter of all hospital charges in the United States can be attributed to the treatment of sepsis.

  (Source: JAMA)

• Community hospitals across the U.S. are spending $55 million a day on sepsis care, according to the most recent published data.

  (Source: CDC)

• A federal analysis of 2013 billing data revealed sepsis to be the most expensive condition to treat in the entire U.S. healthcare system, accounting for nearly $24 billion in annual costs.

  (Source: Sepsis Alliance)

• The typical hospital stay for sepsis is approximately twice the cost of an average hospital stay.

  (Source: CDC)

• Cost savings of up to $1 billion per quality life year gained can be attained with critical care management of severe sepsis, acute respiratory failure, and general critical care interventions.

  (Source: Society of Critical Care Medicine)

• The annual growth rate of sepsis costs is three-times the rate of overall hospital cost increases.

  (Source: CDC)

Sepsis’ Impact On Hospital Performance Outcomes

• Sepsis occurred in just 10% of U.S. hospital patients but contributed to as many as half of all hospital deaths between 2010 and 2012.

  (Source: JAMA)

• Prospective cohort study of over two million patients finds those with any form of sepsis have three times the risk of having a postoperative arterial or venous thrombosis compared to patients without any systemic inflammation.

  (Source: The British Medical Journal)

• General surgery patients appear to have a 10 times greater risk of dying of sepsis and septic shock than of pulmonary embolism or myocardial infarction.

  (Source: JAMA Surgery)

• As many as 34.7% to 52% of patients who died in a hospital had sepsis at the time of their death, according to analysis of nationally representative sample.

  (Source: JAMA)

• Sepsis patients stay in the hospital 75% longer than other patients.

  (Source: CDC)

Opportunities Exist to Improve Sepsis Identification, Treatment and Outcomes

• Chart analysis conducted in a 475-bed university-affiliated hospital found each hour of delay in administering antibiotics resulted in a 7.6% average decrease in survival.

  (Source: PubMed)

• Automated solution detects sepsis in its early stage using predictive analytics to analyze lab results and pharmaceutical order data—all without requiring staff observations of vital signs.

  (Source: Uniphy Health)

• Uniphy Sentinel is the commercially available version of a sepsis alerting system originally developed using a proprietary Military Acuity Model™ to identify Tasks-at-Risk®. This precursor to Sentinel is credited with an 87 percent increase in lives saved.

  (Source: Uniphy Health)